To learn more about responsible cannabis use, visit our resource center. Additionally, we recommend becoming a Happy Valley insider to stay informed on new products and cultivars at our Massachusetts dispensaries. We aim to support the widest array of browsers and assistive technologies as possible, so our users can choose the best fitting tools for them, with as few limitations as possible. Still, recent studies have opened up a new possibility—that genetics are the reason why CHS hits some cannabis consumers but not others. What has never been clear was why only some heavy users of cannabis seem to be affected. While often excluded from this list, one study found that 23% of presentations involve diarrhea at this stage, increasing the potential for misdiagnosis as gastroenteritis.
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The only known permanent cure for Cannabinoid Hyperemesis Syndrome (CHS) is complete abstinence from cannabis. One study looking at Reddit posts on the subject found that spicy food, greasy food, coffee, black tea, and alcohol were frequently mentioned as CHS triggers. These foods/beverages are mostly acidic, but relationships between them and CHS have not been studied scientifically, although the co-use of weed and alcohol is well-known, the study authors said. Your doctor may ask you questions, like how long you’ve been using cannabis and what type of products you normally use. For example, if you smoke weed, eat edibles, use tinctures, or dab or vape THC, tell your doctor about any or all of them.
The Recovery Phase:
A combination of prescribed pharmaceuticals and OTC pain relievers used as recommended can manage symptoms.1 With continued abstinence and symptom management, full recovery can follow. Still, others fault cannabis products themselves, suggesting that excessive THC or commercial pesticides might trigger the condition. While marijuana seems to bring on nausea in the stomach, in the brain it usually has opposite effect. When cannabinoids bind with brain receptors, they tend to prevent nausea and vomiting. There exists no epidemiological data regarding the incidence and prevalence of CHS among chronic marijuana users. The syndrome is likely underreported given its recent recognition 74,75.
- This may include providing information about potential cognitive, psychiatric, and physical harms of cannabis use, plus clear patient-centric recommendations.
- THC exhibits an anti-emetic effect in the central nervous system.
- (Recreational use and sale of cannabis in Canada was legalized starting in 2018).
- The importance of cannabis cessation cannot be overstated, as it remains the only definitive cure.
- The syndrome is likely underreported given its recent recognition 74,75.
Treatment for CHS
Cannabinoid Hyperemesis Syndrome (CHS) is a condition that involves recurrent nausea and vomiting. It is mainly caused by prolonged cannabis use, along with cramping abdominal pain. For https://ecosoberhouse.com/ those who regularly use cannabis, the onset of CHS can be unexpected and bewildering. The symptoms can be intense, with severe vomiting and abdominal discomfort becoming a daily ordeal. As it progresses, the cycle of nausea, vomiting, dehydration, diarrhea, and abdominal pain becomes more frequent, and patients may attempt to self-medicate.
- Cannabinoid hyperemesis syndrome is divided into three different phases, which are described in a 2013 article from Hospital Pharmacy journal.
- Awareness and education about CHS can help individuals recognize the symptoms early and seek appropriate treatment.
- A particularly distressing symptom is ‘scromiting,’ a term describing episodes of extreme vomiting accompanied by screaming due to the pain.
- CB2 receptors are likely involved in the inhibition of inflammation, visceral pain, and intestinal motility in the inflamed gut 9,14.
Recent research published in the Journal of Medical Toxicology suggests this behavior relates to how temperature affects the hypothalamus, where many cannabinoid receptors are located. The hot water appears to temporarily correct the dysregulation of the body’s temperature control and nausea centers caused by chronic cannabis use. Cannabis Hyperemesis Syndrome (CHS) is a rare but important condition that can affect long-term, frequent cannabis users. It manifests through recurrent episodes of severe nausea, vomiting, and abdominal pain. While cannabis is widely recognized for its therapeutic benefits, including its antiemetic (anti-nausea) properties, CHS represents a unique and paradoxical response in a small subset of users. Understanding CHS can help individuals make informed decisions about their cannabis use and maintain their overall well-being.
The majority of these individuals are less than nineteen years of age 2. Similarly in Europe, cannabis use is prominent among young adults, with a prevalence that has increased from 5% in 1990 to 15% in 2005 3. Sober living home While the overall prevalence of marijuana use has remained stable in the United States at 4%, the prevalence of cannabis use disorders (i.e. cannabis dependence, cannabis abuse) has continued to rise 4.
- With the first use of marijuana, the signals from the brain may be more important.
- The only proven way to prevent cannabis hyperemesis syndrome is to avoid cannabis (marijuana).
- Take the first step toward addiction treatment by contacting us today.
- Haloperidol and topical capsaicin have pathophysiologic bases and evidence for use in CHS.
- If you feel unwell or anxious after consuming cannabis but are not a long-term or frequent consumer, read more about what to do if you take too much.
- Here is what pediatric health care providers need to know about this often debilitating disorder.
- CBD enhances the expression of CB1 receptors in the hypothalamus and amplifies the hypothermic effects caused by THC 29.
- Understanding CHS is crucial for both medical professionals and individuals who use cannabis, as early recognition can prevent serious complications and improve outcomes.
One study found a median time of 8 years from symptoms beginning to diagnosis – with some patients going up to 21 years with symptoms before a CHS diagnosis. Patients in that study went to the ER an average of 22 times for their symptoms before getting a diagnosis. The Bluffs is a private alcohol, substance abuse and mental health treatment facility located in central Ohio. CannaMD is committed to providing compassionate care to Florida patients through evidence-based application of medical cannabis research. Centered around education, empathy, and exceptional customer service, CannaMD offers an unparalleled patient experience – empowering Florida residents to pursue a better quality of life.
CB1 receptor activation in the hypothalamus and pituitary gland results in modulation of all hypothalamic-pituitary axes 38. Receptor activation leads to inhibitory effects on the release of growth hormone, thyroid hormone, prolactin, and luteinizing hormone 38. In animal studies mice lacking CB1 receptors demonstrate enhancement in circadian HPA axis activity peaks and impairment in glucocorticoid feedback 39. Two well-characterized naturally occurring endocannabinoids are anandamide and 2-arachidonoylglycerol. Cannabinoids discovered in the cannabis plant with known effects on the regulation of emesis include tetrahydrocannabinol, chs hyperemetic phase cannabidiol, and cannabigerol. Along with the discovery of the CB1 and CB2 receptors has been the identification of endogenous arachidonic acid derivatives that bind to these receptors (Figure 1).